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Polarityte Inc / BioTech Discussion

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jusken:

--- Quote from: kavan on October 06, 2017, 04:13:26 PM ---Cambridge investments was listed as major share holder. (I'm from Cambridge and went to schools and colleges there.) So, I was trying to see where in Cambridge it was. Bio-tech firms are often kind of close to MIT campus on Kendall square side. I think the main company marketing their 'break through' is in Utah but the company called 'Cambridge' investments owning most of the shares is in Iowa.

It's like this:  If a bio tech firm is actually in Camb. MA, they often have an MIT or MGH connection or at least there is a lot of overlap. Even if an investment firm in bio tech stuff is there. But the major share holder was in a corn field (well maybe an apple orchard) somewhere in Iowa.

Anyway, big name in tissue regeneration is Dr. Vacanti at MGH https://hsci.harvard.edu/people/joseph-vacanti-md.  There are other names. But if you don't have way to know 'who's who' in that field, it's hard to make heads or tails of these start ups because a good marker is WHO is involved.

Not totally sure but I just tend to think what ever their 'proprietary breakthrough' is, is probably from PRIOR stem cell research where there are tons of papers on wound healing methods or just something they can claim as a breakthrough to investors who don't have much of a science background.  Basics of wound healing is good debridement and MOIST healing. Add some stem cells or maybe some platelet rich plasma and your good to go. That said, not too sure this outfit is on the verge of any true breakthrough.

--- End quote ---

Interesting stuff, good to know.

I'm not sure how useful looking at this as a medical breakthrough is. There are a lot of similar companies working on similar problems, and it's unlikely that they're doing something totally novel in terms of research.  A lot of science is out there that has been waiting on human testing.  I believe this is the first to go to human trials with the aim of regrowing layers of skin/hair, though I'm just an enthusiastic outsider. This sounds like hopeful news for someone suffering bad skin afflictions - or possibly tangential therapies?

Perhaps it's just the most well marketed?  This is definitely a good time to market for Biotech given the recent surge and obviously that means a lot of potential quackery.

GJ: maybe include my initial post so it includes the link?

GJ:

--- Quote from: jusken on October 06, 2017, 05:13:56 PM ---GJ: maybe include my initial post so it includes the link?

--- End quote ---

It was already in there, but you bring up a good point, and so I did ad a description how this was split from the other thread so people aren't confused.

BTW, the reason I split it is I'd like that Regenerative Medicine thread to be easy access where people can just come in and find things instead having to sift through a lot of discussion/tangents.

BioTech is interesting...I hope they can regrow papilla and teeth. It's odd nature gave us the ability to regrow things like fingernails and toenails but not teeth/gums, which are way more important. 

kavan:

--- Quote from: jusken on October 06, 2017, 05:13:56 PM ---Interesting stuff, good to know.

I'm not sure how useful looking at this as a medical breakthrough is. There are a lot of similar companies working on similar problems, and it's unlikely that they're doing something totally novel in terms of research.  A lot of science is out there that has been waiting on human testing.  I believe this is the first to go to human trials with the aim of regrowing layers of skin/hair, though I'm just an enthusiastic outsider. This sounds like hopeful news for someone suffering bad skin afflictions - or possibly tangential therapies?

Perhaps it's just the most well marketed?  This is definitely a good time to market for Biotech given the recent surge and obviously that means a lot of potential quackery.

GJ: maybe include my initial post so it includes the link?

--- End quote ---

Oops. I must have been the one who went on a tangent.

Ken, are you an investor or someone hopeful for advancements in this venue?  There is a lot of stuff about stem cells from fat being used in a bunch of different regeneration modalities. If it's cosmetic skin repair, there is already different kinds of fat grafting and platelet rich plasma and 'stromal cells' out there in use for things like that.

jusken:
Definitely not an investor, don't know enough about it.

I've been looking into bone/tissue advancements.  After jaw surgery, my teeth and gums in particular have black triangles/bone loss.  I also looked into fat grafting for a couple years because of the embarrassment being so gaunt (particularly in the face) has caused me.  I've come to the conclusion that the current treatment modalities are fairly arcane.  Grafting in general is just very unpredictable, as well as being highly limited in where it can treat (resulting in only a partial correction).

I have a few companies I've been following, this one popped up several months ago and is going to human trials.  If you have any others that I don't know about, I'm definitely interested!

GJ:

--- Quote from: jusken on October 06, 2017, 06:02:51 PM ---After jaw surgery, my teeth and gums in particular have black triangles/bone loss.
--- End quote ---

That's me, you, and Lazlo at the least.

It's bad how that happens. I think it's mostly the orthodontics, and they don't tell you this going into it. I really hope they can regrow bone/papilla within the next decade. The George Bush years were really lean for stem cell based BioTech because he had to pretend to be against stem cells to keep certain voters. Stem Cell behavior and technology are pretty amazing.

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